IQSEC2 Antikörper (AA 851-950) (AbBy Fluor® 555)
-
- Target Alle IQSEC2 Antikörper anzeigen
- IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
-
Bindungsspezifität
- AA 851-950
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IQSEC2 Antikörper ist konjugiert mit AbBy Fluor® 555
-
Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IQSEC2
- Isotyp
- IgG
- Top Product
- Discover our top product IQSEC2 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
- Andere Bezeichnung
- IQSEC2 (IQSEC2 Produkte)
- Synonyme
- BRAG1 antikoerper, MRX1 antikoerper, Brag1 antikoerper, mKIAA0522 antikoerper, RGD1562109 antikoerper, IQ motif and Sec7 domain 2 antikoerper, IQSEC2 antikoerper, Iqsec2 antikoerper
- Hintergrund
-
Synonyms: BRAG1, IQ mot and SEC7 domain-containing protein 2, IQEC2_HUMAN, Iqsec2, KIAA0522, mKIAA0522, MRX1, RP11-258C19.1.
Background: IQSEC2 is a 1,478 amino acid protein that belongs to the BRAG family and contains one IQ domain, one PH domain and a SEC7 domain. Localizing to the cytoplasm, IQSEC2 is expressed in brain, kidney and small intestine, with weaker levels of expression in placenta, pancreas, ovary, prostate and liver. IQSEC2 is a component of the postsynaptic density at excitatory synapses, and interacts with ARF family members as a guanine nucleotide exchange factor. Through the activation of ARF substrates, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization. The gene encoding IQSEC2 maps to the human X chromosome. Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), a condition characterized by decreased intellectual function. IQSEC2 exists as three isoforms due to alternative splicing events.
-