ZBTB46 Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1696852

Produktdetails anti-ZBTB46 Antikörper (AbBy Fluor® 555)

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB46 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ZBTB46

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Andere Bezeichnung: Zbtb46/Btbd4 (ZNF340 Produkte)

Hintergrund:

Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.

Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

Gen-ID: 140685