FIP1L1 Antikörper (AA 501-594) (AbBy Fluor® 555)
-
- Target Alle FIP1L1 Antikörper anzeigen
- FIP1L1 (FIP1 Like 1 (FIP1L1))
-
Bindungsspezifität
- AA 501-594
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FIP1L1 Antikörper ist konjugiert mit AbBy Fluor® 555
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FIP1L1
- Isotyp
- IgG
- Top Product
- Discover our top product FIP1L1 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- FIP1L1 (FIP1 Like 1 (FIP1L1))
- Andere Bezeichnung
- FIP1L1 (FIP1L1 Produkte)
- Synonyme
- FIP1 antikoerper, Rhe antikoerper, hFip1 antikoerper, 1300019H17Rik antikoerper, Rje antikoerper, fip1l1 antikoerper, wu:fd36f11 antikoerper, zgc:103421 antikoerper, factor interacting with PAPOLA and CPSF1 antikoerper, factor interacting with PAPOLA and CPSF1 S homeolog antikoerper, FIP1 like 1 (S. cerevisiae) antikoerper, FIP1 like 1b (S. cerevisiae) antikoerper, fip1l1 antikoerper, FIP1L1 antikoerper, fip1l1.S antikoerper, Fip1l1 antikoerper, fip1l1b antikoerper
- Hintergrund
-
Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.
Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.
- Gen-ID
- 81608
-