PBX4 Antikörper (AA 201-320) (AbBy Fluor® 555)

Produktnummer ABIN1697348

Produktdetails anti-PBX4 Antikörper (AbBy Fluor® 555)

Target: PBX4 (Pre-B-Cell Leukemia Homeobox 4 (PBX4))

Bindungsspezifität: AA 201-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PBX4 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PBX4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PBX4

Target: PBX4 (Pre-B-Cell Leukemia Homeobox 4 (PBX4))

Andere Bezeichnung: PBX4 (PBX4 Produkte)

Synonyme: PBX4 antikoerper, 2410015M21Rik antikoerper, AI429113 antikoerper, AW045266 antikoerper, Edg4 antikoerper, PBX homeobox 4 antikoerper, pre B cell leukemia homeobox 4 antikoerper, PBX4 antikoerper, Pbx4 antikoerper

Hintergrund:

Synonyms: 2410015M21Rik, AI429113, AW045266, Edg4, Endothelial dferentiation, lysophosphatidic acid G protein coupled receptor 4, Homeobox protein PBX4, OTTMUSP00000045221, PBX4, PBX4_HUMAN, pre-B-cell leukemia homeobox 4, Pre-B-cell leukemia transcription factor 4.

Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

Gen-ID: 80714