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FMN1 Antikörper (AA 651-750) (AbBy Fluor® 555)

FMN1 Reaktivität: Human, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1697410
  • Target Alle FMN1 Antikörper anzeigen
    FMN1 (Formin 1 (FMN1))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 651-750
    Reaktivität
    • 25
    • 15
    • 2
    Human, Ratte
    Wirt
    • 23
    • 3
    Kaninchen
    Klonalität
    • 25
    • 1
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FMN1 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FMN1/Formin 1
    Isotyp
    IgG
    Top Product
    Discover our top product FMN1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FMN1 (Formin 1 (FMN1))
    Andere Bezeichnung
    FMN1/Formin 1 (FMN1 Produkte)
    Synonyme
    si:dkey-81b15.10 antikoerper, fmn antikoerper, formin antikoerper, FMN antikoerper, LD antikoerper, BB164513 antikoerper, Fmn antikoerper, formin-1 antikoerper, ld antikoerper, RGD1306349 antikoerper, RGD1310100 antikoerper, formin 1 antikoerper, fmn1 antikoerper, FMN1 antikoerper, Fmn1 antikoerper
    Hintergrund

    Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

    Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

    Gen-ID
    342184
    Pathways
    Regulation of Actin Filament Polymerization
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