SP6 Antikörper (AA 201-300) (AbBy Fluor® 555)

Produktnummer ABIN1697750

Produktdetails anti-SP6 Antikörper (AbBy Fluor® 555)

Target: SP6 (Sp6 Transcription Factor (SP6))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP6 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SP6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SP6

Target: SP6 (Sp6 Transcription Factor (SP6))

Andere Bezeichnung: SP6 (SP6 Produkte)

Hintergrund:

Synonyms: MGC119665, Epfn, EPIPROFIN, KLF14, Krueppel-like factor 14, MGC119662, MGC119663, MGC119664, Sp6, Sp6 transcription factor, SP6_HUMAN, Transcription factor Sp6.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96 % sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.