Orexin A Antikörper (AbBy Fluor® 647)

Produktnummer ABIN1698249

Produktdetails anti-Orexin A Antikörper (AbBy Fluor® 647)

Target: Orexin A (OXA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Orexin A Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Orexin A

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Orexin A

Target: Orexin A (OXA)

Andere Bezeichnung: Orexin A (OXA Produkte)

Synonyme: PPOX antikoerper, orexin-A antikoerper, hypocretin antikoerper, hypocretin neuropeptide precursor antikoerper, Hcrt antikoerper, HCRT antikoerper

Hintergrund:

Synonyms: HCRT 1, HCRT, HCRT1, HCRT2, Hypocretin orexin neuropeptide precursor, Hypocretin 1, Hypocretin 2, Hypocretin A, Hypocretin, Hypocretin neuropeptide precursor, Hypocretin1, NRCLP1, Orexin A, Orexin, Orexin B, Orexin precursor, OrexinA, OX, PPORX, PPOX, PREPROOREXIN, OREX_HUMAN.

Background: Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

Gen-ID: 3060

Pathways: Synaptic Membrane, Feeding Behaviour