SH2B3 Antikörper (AA 161-260) (AbBy Fluor® 647)
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- Target Alle SH2B3 Antikörper anzeigen
- SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
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Bindungsspezifität
- AA 161-260
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SH2B3 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Monkey
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LNK
- Isotyp
- IgG
- Top Product
- Discover our top product SH2B3 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SH2B3 (SH2B Adaptor Protein 3 (SH2B3))
- Andere Bezeichnung
- LNK (SH2B3 Produkte)
- Synonyme
- LNK antikoerper, IDDM20 antikoerper, AI429800 antikoerper, Lnk antikoerper, SH2B adaptor protein 3 antikoerper, SH2B3 antikoerper, Sh2b3 antikoerper
- Hintergrund
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Synonyms: IDDM20,Lymphocyte adapter protein,Lymphocyte specic adapter protein,Lymphocyte specic adapter protein Lnk,Lymphocyte-specic adapter protein Lnk,SH2B adapter protein 3,SH2B adaptor protein 3,Sh2b3,SH2B3_HUMAN,Signal transduction protein Lnk.
Background: APS (adapter molecule containing PH and SH2 domains), SH2-B and Lnk compose a family of adapter proteins, which contain a pleckstrin homology (PH) domain, an SH2 domain and a tyrosine phosphorylation site. Stimulation of B cell receptor (BCR) or T cell receptor (TCR) results in the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of BCR, TCR and several substrates. APS, SH2-B and Lnk may bind to the ITAM domain of BCR and TCR. Lnk is tyrosine phosphorylated in response to TCR stimulation and APS has been shown to be tyrosine phosphorylated in response to BCR stimulation.
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