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MYCBPAP Antikörper (AA 401-500) (AbBy Fluor® 647)

MYCBPAP Reaktivität: Ratte, Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN1698552
  • Target Alle MYCBPAP Antikörper anzeigen
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Bindungsspezifität
    • 14
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 16
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYCBPAP Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYCBPAP
    Isotyp
    IgG
    Top Product
    Discover our top product MYCBPAP Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Andere Bezeichnung
    MYCBPAP (MYCBPAP Produkte)
    Synonyme
    AMAP-1 antikoerper, AMAP1 antikoerper, 4932408B01Rik antikoerper, AW125474 antikoerper, COD106 antikoerper, MYCBP associated protein antikoerper, Mycbp associated protein antikoerper, MYCBPAP antikoerper, Mycbpap antikoerper
    Hintergrund

    Synonyms: AMAM-1, AMAP-1, AMAP1, AMY-1-binding protein 1, DKFZp434N1415, MYBPP_HUMAN, MYCBP-associated protein, Mycbpap.

    Background: AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Pathways
    Sensory Perception of Sound
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