m1ip1 Antikörper (AA 21-120) (AbBy Fluor® 647)

Produktnummer ABIN1698585

Produktdetails anti-m1ip1 Antikörper (AbBy Fluor® 647)

Target: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Bindungsspezifität: AA 21-120

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser m1ip1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu m1ip1

Target: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Andere Bezeichnung: SLAP (m1ip1 Produkte)

Synonyme: MIG12 antikoerper, TB10 antikoerper, G12-like antikoerper, S14R antikoerper, STRAIT11499 antikoerper, THRSPL antikoerper, 3110038L01Rik antikoerper, Mig12 antikoerper, slap antikoerper, mig12 antikoerper, thrspl antikoerper, MGC80850 antikoerper, zgc:73223 antikoerper, g12 antikoerper, wu:fj32f05 antikoerper, thymosin beta 10 antikoerper, MID1 interacting protein 1 antikoerper, Mid1-interacting protein 1 antikoerper, Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) antikoerper, MID1 interacting protein 1 S homeolog antikoerper, MID1 interacting protein 1b antikoerper, MID1 interacting protein 1a antikoerper, TMSB10 antikoerper, MID1IP1 antikoerper, m1ip1 antikoerper, Mid1ip1 antikoerper, mid1ip1.S antikoerper, mid1ip1b antikoerper, mid1ip1a antikoerper

Hintergrund:

Synonyms: hSLAP, SLA 1, SLA, SLA1, SLAP 1, SLAP, SLAP-1, SLAP1, SLAP1_HUMAN, Src like adapter, Src like adapter protein 1, Src like adaptor, SRC-like-adapter, Src-like-adapter protein 1.

Background: The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.