GAS41 Antikörper (AA 151-227) (AbBy Fluor® 647)

Produktnummer ABIN1698684

Dieses Anti-GAS41-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GAS41 in WB, IF (cc) und IF (p). Geeignet für Maus und Xenopus laevis.

Kurzübersicht für GAS41 Antikörper (AA 151-227) (AbBy Fluor® 647) (ABIN1698684)

Target: GAS41 (YEATS Domain Containing 4)

Reaktivität: Maus, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAS41 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GAS41 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 151-227

Kreuzreaktivität: Maus, Xenopus laevis

Homologie: Human,Rat,Cow,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GAS41

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GAS41

Target: GAS41 (YEATS Domain Containing 4)

Andere Bezeichnung: GAS41

Hintergrund:

Synonyms: 4930573H17Rik, B230215M10Rik, GAS 41, Gas41, glioma amplied sequence 41, Glioma-amplied sequence 41, glioma-amplied sequence-41, gliomaamplied sequence 41, gliomaamplied sequence41, NUBI 1, NuBI-1, NuBI1, NuMA binding protein 1, NuMA-binding protein 1, YAF9, YEATS domain containing 4, YEATS domain containing4, YEATS domain-containing protein 4, YEATS4, YETS4_HUMAN.

Background: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias, and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (Integrase Interactor), which is a human homologue of the yeast SNF5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.

Gen-ID: 8089