ARID1B Antikörper (AA 1501-1600) (AbBy Fluor® 647)
-
- Target Alle ARID1B Antikörper anzeigen
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
-
Bindungsspezifität
- AA 1501-1600
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ARID1B Antikörper ist konjugiert mit AbBy Fluor® 647
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ARID1B
- Isotyp
- IgG
- Top Product
- Discover our top product ARID1B Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
- Andere Bezeichnung
- ARID1B (ARID1B Produkte)
- Synonyme
- fd07d11 antikoerper, si:dkey-60a16.3 antikoerper, wu:fd07d11 antikoerper, 8030481M12 antikoerper, 9330189K18Rik antikoerper, AI836955 antikoerper, Ardi1b antikoerper, B230217J03Rik antikoerper, mKIAA1235 antikoerper, 6A3-5 antikoerper, Smcf1 antikoerper, smcf-1 antikoerper, BAF250B antikoerper, BRIGHT antikoerper, DAN15 antikoerper, ELD/OSA1 antikoerper, MRD12 antikoerper, OSA2 antikoerper, P250R antikoerper, AT rich interactive domain 1B (SWI1-like) antikoerper, AT rich interactive domain 1B (SWI-like) antikoerper, AT-rich interaction domain 1B antikoerper, arid1b antikoerper, Arid1b antikoerper, ARID1B antikoerper
- Hintergrund
-
Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235
Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
- Gen-ID
- 57492
- UniProt
- Q8NFD5
-