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LIMD1 Antikörper (AA 21-120) (AbBy Fluor® 647)

LIMD1 Reaktivität: Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN1699002
  • Target Alle LIMD1 Antikörper anzeigen
    LIMD1 (LIM Domains Containing 1 (LIMD1))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 33
    • 21
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 40
    • 2
    Kaninchen
    Klonalität
    • 40
    • 2
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LIMD1 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 25
    • 19
    • 17
    • 12
    • 12
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Limd1
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    LIMD1 (LIM Domains Containing 1 (LIMD1))
    Andere Bezeichnung
    Limd1 (LIMD1 Produkte)
    Synonyme
    AW822033 antikoerper, D9Ertd192e antikoerper, xlimd1 antikoerper, LIM domains containing 1 antikoerper, LIM domains containing 1 L homeolog antikoerper, LIMD1 antikoerper, Limd1 antikoerper, limd1 antikoerper, limd1.L antikoerper
    Hintergrund

    Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.

    Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.

    Gen-ID
    8994
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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