C8orf48 Antikörper (AA 251-319) (Biotin)

Produktnummer ABIN1699941

Produktdetails anti-C8orf48 Antikörper (Biotin)

Target: C8orf48 (Chromosome 8 Open Reading Frame 48 (C8orf48))

Bindungsspezifität: AA 251-319

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C8orf48 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C8orf48

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C8orf48

Target: C8orf48 (Chromosome 8 Open Reading Frame 48 (C8orf48))

Andere Bezeichnung: C8orf48 (C8orf48 Produkte)

Synonyme: chromosome 8 open reading frame 48 antikoerper, C8orf48 antikoerper

Hintergrund:

Synonyms: C8orf48, CH048_HUMAN, Chromosome 8 open reading frame 48, FLJ25402, Uncharacterized protein C8orf48.

Background: C8orf48 (chromosome 8 open reading frame 48) is a 319 amino acid protein encoded by a gene that maps to human chromosome 8p22. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Gen-ID: 157773