GPR77 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1700016

Produktdetails anti-GPR77 Antikörper (Biotin)

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR77 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPF77

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Andere Bezeichnung: GPR77 (GPR77 Produkte)

Synonyme: GPR77 antikoerper, C5L2 antikoerper, GPF77 antikoerper, E030029A11Rik antikoerper, Gpr77 antikoerper, complement component 5a receptor 2 antikoerper, C5AR2 antikoerper, C5ar2 antikoerper

Hintergrund:

Synonyms: C5a anaphylatoxin chemotactic receptor C5L2, C5ARL_HUMAN, C5L2, E030029A11Rik, G protein coupled receptor 77, G protein coupled receptor C5L2, G-protein coupled receptor 77, GPF77, GPR77, GPCR GPR77.

Background: Anaphylatoxin, a chemotactic and inflammatory peptide, is a receptor for C5a anaphylatoxin chemotactic receptor (C5L2), also designated G protein-coupled receptor 77. C5L2 is an integral membrane protein that belongs to the Gprotein-coupled receptor 1 family. C5L2 weakly couples to Gi-mediated signaling pathways and is widely expressed in the hippocampus, hypothalamus, pons, frontal cortex and liver. It is coexpressed with the C5a receptor (C5AR) on polymorphonuclear neutrophils and may modulate the activity of C5AR. The function of the C5a receptors, particularly that of C5L2, is still unclear. Research suggests that C5L2 may be required for the in vitro release of high mobility group box 1 protein (HMGB1).

Gen-ID: 27202