MED23 Antikörper (AA 401-500) (Biotin)

Produktnummer ABIN1700159

Produktdetails anti-MED23 Antikörper (Biotin)

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Bindungsspezifität: AA 401-500

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED23 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DRIP130/CRSP130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MED23

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Andere Bezeichnung: DRIP130/CRSP130 (MED23 Produkte)

Synonyme: CG3695 antikoerper, Dmel\\CG3695 antikoerper, Gal11/SUR2 antikoerper, Med23 antikoerper, Trap150 antikoerper, Trap150beta antikoerper, dSUR2 antikoerper, dTRAP150beta antikoerper, CRSP3 antikoerper, MED23 antikoerper, ARC130 antikoerper, CRSP130 antikoerper, CRSP133 antikoerper, DRIP130 antikoerper, MRT18 antikoerper, SUR-2 antikoerper, SUR2 antikoerper, 130kDa antikoerper, 3000002A17Rik antikoerper, Crsp3 antikoerper, ESTM7 antikoerper, Sur2 antikoerper, X83317 antikoerper, mKIAA1216 antikoerper, crsp3 antikoerper, si:ch211-272f15.2 antikoerper, zgc:91979 antikoerper, Mediator complex subunit 23 antikoerper, mediator complex subunit 23 antikoerper, mediator of RNA polymerase II transcription subunit 23 antikoerper, mediator complex subunit 23 L homeolog antikoerper, Mediator of RNA polymerase II transcription subunit 23 antikoerper, MED23 antikoerper, med23 antikoerper, LOC412332 antikoerper, Med23 antikoerper, med23.L antikoerper, sur-2 antikoerper

Hintergrund:

Synonyms: 130 kDa transcriptional co activator, 133 kDa transcriptional co activator, Activator recruited cofactor 130 kDa component, Activator-recruited cofactor 130 kDa component, ARC 130, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa mediator, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP 130, CRSP 130 kD subunit, CRSP 133, CRSP 3, CRSP complex subunit 3, CRSP130, CRSP133, CRSP3, CRSP3 protein, DKFZp434H0117, DRIP 130, DRIP130, hSur-2, KIAA1216, MED 23, MED23, MED23_HUMAN, Mediator complex subunit 23, Mediator of RNA polymerase II transcription subunit 23, Protein sur-2 homolog, SUR 2, SUR2, Transcriptional co activator CRSP 130, Transcriptional co activator CRSP130, Transcriptional coactivator CRSP130, Vitamin D3 receptor interacting protein, Vitamin D3 receptor interacting protein complex 130 kDa component, Vitamin D3 receptor-interacting protein complex 130 kDa component.

Background: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1 (2). CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits (3). Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS (4). CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins (2,5). CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription (6,7).

Gen-ID: 9439

Pathways: Regulation of Lipid Metabolism by PPARalpha