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C1orf177 Antikörper (AA 21-100) (Biotin)

C1ORF177 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700214
  • Target Alle C1orf177 (C1ORF177) Produkte
    C1orf177 (C1ORF177) (Chromosome 1 Open Reading Frame 177 (C1ORF177))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    AA 21-100
    Reaktivität
    • 31
    • 19
    • 16
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser C1orf177 Antikörper ist konjugiert mit Biotin
    Applikation
    • 26
    • 20
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf177
    Isotyp
    IgG
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    C1orf177 (C1ORF177) (Chromosome 1 Open Reading Frame 177 (C1ORF177))
    Andere Bezeichnung
    C1orf177 (C1ORF177 Produkte)
    Synonyme
    lymphocyte expansion molecule antikoerper, lymphocyte expansion molecule L homeolog antikoerper, LEXM antikoerper, lexm.L antikoerper
    Hintergrund

    Synonyms: Chromosome 1 open reading frame 177, FLJ40201, Hypothetical protein LOC163747, Uncharacterized protein C1orf177, CA177_HUMAN.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.

    Gen-ID
    163747
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