C2ORF54 Antikörper (AA 361-447) (Biotin)

Produktnummer ABIN1700221

Produktdetails anti-C2ORF54 Antikörper (Biotin)

Target: C2ORF54 (Chromosome 2 Open Reading Frame 54 (C2ORF54))

Bindungsspezifität: AA 361-447

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C2ORF54 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf54

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C2ORF54

Target: C2ORF54 (Chromosome 2 Open Reading Frame 54 (C2ORF54))

Andere Bezeichnung: C2orf54 (C2ORF54 Produkte)

Synonyme: chromosome 2 open reading frame 54 antikoerper, C2orf54 antikoerper

Hintergrund:

Synonyms: C2orf54, CB054_HUMAN, Chromosome 2 open reading frame 54, Uncharacterized protein C2orf54.

Background: C2orf54 (chromosome 2 open reading frame 54), also known as FLJ22671, MGC150431 or MGC150432, is a 447 amino acid protein that exists as three alternatively spliced isoforms, which are encoded by a gene located on human chromosome 2q37.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gen-ID: 79919