C6orf70 Antikörper (AA 151-250) (Biotin)

Produktnummer ABIN1700226

Produktdetails anti-C6orf70 Antikörper (Biotin)

Target: C6orf70 (ERMARD) (ER Membrane-Associated RNA Degradation (ERMARD))

Bindungsspezifität: AA 151-250

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C6orf70 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf70

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C6orf70

Target: C6orf70 (ERMARD) (ER Membrane-Associated RNA Degradation (ERMARD))

Andere Bezeichnung: C6orf70 (ERMARD Produkte)

Synonyme: C6orf70 antikoerper, dJ266L20.3 antikoerper, ER membrane associated RNA degradation antikoerper, ERMARD antikoerper

Hintergrund:

Synonyms: C6orf70, CF070_HUMAN, Chromosome 6 open reading frame 70, dJ266L20.3, FLJ11152, OTTHUMP00000017683, RP1-266L20.6, Transmembrane protein C6orf70.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf70 gene product has been provisionally designated C6orf70 pending further characterization.

Gen-ID: 55780