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Chloride Channel 5 Antikörper (AA 1-100) (Biotin)

CLCN5 Reaktivität: Human ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700244
  • Target Alle Chloride Channel 5 (CLCN5) Antikörper anzeigen
    Chloride Channel 5 (CLCN5)
    Bindungsspezifität
    • 14
    • 14
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 48
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 48
    • 1
    Kaninchen
    Klonalität
    • 49
    Polyklonal
    Konjugat
    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Chloride Channel 5 Antikörper ist konjugiert mit Biotin
    Applikation
    • 23
    • 21
    • 13
    • 13
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
    Isotyp
    IgG
    Top Product
    Discover our top product CLCN5 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Chloride Channel 5 (CLCN5)
    Andere Bezeichnung
    Chloride Channel 5 (CLCN5 Produkte)
    Synonyme
    CLCN3 antikoerper, CLCN5 antikoerper, clcn5-A antikoerper, DKFZp469O2315 antikoerper, 5430408K11Rik antikoerper, ClC-5 antikoerper, Clc5 antikoerper, D930009B12Rik antikoerper, DXImx42e antikoerper, Sfc13 antikoerper, T25545 antikoerper, CLC5 antikoerper, CLCK2 antikoerper, DENTS antikoerper, NPHL1 antikoerper, NPHL2 antikoerper, XLRH antikoerper, XRN antikoerper, hCIC-K2 antikoerper, CLCN4 antikoerper, Clcn5 antikoerper, chloride voltage-gated channel 5 antikoerper, chloride channel, voltage-sensitive 5 L homeolog antikoerper, chloride channel, voltage-sensitive 5 antikoerper, CLCN5 antikoerper, clcn5.L antikoerper, clcn5 antikoerper, Clcn5 antikoerper
    Hintergrund

    Synonyms: Chloride channel protein 5, Chloride transporter ClC-5, ClC-5, CLC5, CLCK2, CLCN5, CLCN5_HUMAN, DENTS, H+/Cl- exchange transporter 5, hCIC-K2, NPHL1, NPHL2, XLRH, XRN.

    Background: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent?s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.

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