NUP210 Antikörper (AA 1161-1260) (Biotin)

Produktnummer ABIN1700321

Produktdetails anti-NUP210 Antikörper (Biotin)

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Bindungsspezifität: AA 1161-1260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP210 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GP210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NUP210

Target: NUP210 (Nucleoporin 210kDa (NUP210))

Andere Bezeichnung: GP210 (NUP210 Produkte)

Synonyme: 9830001L10 antikoerper, AI836801 antikoerper, Pom210 antikoerper, gp190 antikoerper, gp210 antikoerper, GP210 antikoerper, POM210 antikoerper, nucleoporin 210 antikoerper, nucleoporin 210kDa L homeolog antikoerper, NUP210 antikoerper, Nup210 antikoerper, nup210.L antikoerper

Hintergrund:

Synonyms: FLJ22389, GP 210, KIAA0906, Nuclear envelope pore membrane protein POM 210, Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nucleoporin 210, Nucleoporin 210 kDa, Nucleoporin Nup210, Nucleoporin210, NUP 210, NUP210, PO210_HUMAN, POM 210, POM210, Pore membrane protein of 210 kDa.

Background: The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). gp210, also known as Nup210 (nucleoporin 210 kDa) or POM210, is a 1,887 amino acid single-pass type I membrane protein that localizes to both the endoplasmic reticulum and to the nucleus, specifically within the NPC. Expressed ubiquitously with highest expression in pancreas, testis, lung, ovary and liver, gp210 functions as a nucleoporin that is capable of dimerization and is essential for the assembly, fusion and structural integrity of the NPC. gp210 exists as multiple alternatively spliced isoforms and is subject to post-translational phosphorylation.

Gen-ID: 23225

UniProt: Q8TEM1

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion