NCKAP5 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1700366

Produktdetails anti-NCKAP5 Antikörper (Biotin)

Target: NCKAP5 (NCK Associated Protein 5 (NCKAP5))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCKAP5 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCKAP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NCKAP5

Target: NCKAP5 (NCK Associated Protein 5 (NCKAP5))

Andere Bezeichnung: NCKAP5 (NCKAP5 Produkte)

Synonyme: ERIH1 antikoerper, ERIH2 antikoerper, NAP5 antikoerper, 8430408F21 antikoerper, D130011D22Rik antikoerper, E030049G20Rik antikoerper, Erih1 antikoerper, Erih2 antikoerper, Gm1548 antikoerper, Nap5 antikoerper, RGD1564507 antikoerper, NCK associated protein 5 antikoerper, NCK-associated protein 5 antikoerper, NCKAP5 antikoerper, Nckap5 antikoerper

Hintergrund:

Synonyms: ERIH1, ERIH2, NAP-5, NAP5, Nck-associated protein 5, NCKAP5, NCKP5_HUMAN, Peripheral clock protein.

Background: NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is due to mutations in the ALMS1 gene.