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NOB1 Antikörper (Biotin)

NOB1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700369
  • Target Alle NOB1 Antikörper anzeigen
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    Reaktivität
    • 52
    • 23
    • 20
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 51
    • 2
    Kaninchen
    Klonalität
    • 51
    • 2
    Polyklonal
    Konjugat
    • 21
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NOB1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 43
    • 20
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NOB1
    Isotyp
    IgG
    Top Product
    Discover our top product NOB1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    Andere Bezeichnung
    NOB1 (NOB1 Produkte)
    Synonyme
    MEE6.26 antikoerper, MEE6_26 antikoerper, Nob1p antikoerper, fc27e05 antikoerper, si:ch73-167i17.3 antikoerper, wu:fc27e05 antikoerper, ART-4 antikoerper, MST158 antikoerper, NOB1P antikoerper, PSMD8BP1 antikoerper, 1700021I09Rik antikoerper, Psmd8bp1 antikoerper, NIN1/PSMD8 binding protein 1 homolog antikoerper, RNA-binding NOB1-like protein antikoerper, RNA-binding protein nob1 antikoerper, RNA-binding protein NOB1 antikoerper, NIN1/RPN12 binding protein 1 homolog S homeolog antikoerper, NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) antikoerper, NIN1/RPN12 binding protein 1 homolog antikoerper, NOB1 antikoerper, AT5G41190 antikoerper, EDI_130960 antikoerper, CpipJ_CPIJ012739 antikoerper, BDBG_01281 antikoerper, PAAG_04204 antikoerper, PITG_13300 antikoerper, nob1.S antikoerper, nob1 antikoerper, Nob1 antikoerper
    Hintergrund

    Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.

    Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.

    Gen-ID
    28987
    Pathways
    Protein targeting to Nucleus
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