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PAG1 Antikörper (AA 331-432) (Biotin)

PAG1 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700376
  • Target Alle PAG1 Antikörper anzeigen
    PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
    Bindungsspezifität
    • 15
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-432
    Reaktivität
    • 27
    • 24
    • 23
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 40
    • 4
    Kaninchen
    Klonalität
    • 40
    • 4
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAG1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 31
    • 16
    • 13
    • 13
    • 11
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PAG1
    Isotyp
    IgG
    Top Product
    Discover our top product PAG1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
    Andere Bezeichnung
    PAG1 (PAG1 Produkte)
    Synonyme
    Cbp antikoerper, F730007C19Rik antikoerper, Pag antikoerper, CBP antikoerper, PAG antikoerper, MGC80192 antikoerper, phosphoprotein associated with glycosphingolipid microdomains 1 antikoerper, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 antikoerper, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 L homeolog antikoerper, Pag1 antikoerper, PAG1 antikoerper, pag1.L antikoerper, pag1 antikoerper
    Hintergrund

    Synonyms: CBP, PAG, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, PAG1

    Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

    Gen-ID
    55824
    UniProt
    Q9NWQ8
    Pathways
    p53 Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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