FHOD1 Antikörper (pThr1141) (Biotin)

Produktnummer ABIN1700461

Produktdetails anti-FHOD1 Antikörper (Biotin)

Target: FHOD1 (Formin Homology 2 Domain Containing 1 (FHOD1))

Bindungsspezifität: pThr1141

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FHOD1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FHOD1 around the phosphorylation site of Thr1141

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FHOD1

Target: FHOD1 (Formin Homology 2 Domain Containing 1 (FHOD1))

Andere Bezeichnung: FHOD1 (FHOD1 Produkte)

Synonyme: FHOS antikoerper, BC017144 antikoerper, FHOS1 antikoerper, formin homology 2 domain containing 1 antikoerper, FHOD1 antikoerper, Fhod1 antikoerper

Hintergrund:

Synonyms: FHOD1 phospho T1141, p-FHOD1 phospho T1141, FH1/FH2 domain containing protein, FH1/FH2 domain-containing protein 1, Fhod1, FHOD1_HUMAN, FHOS, FHOS1, Formin homolog overexpressed in spleen 1, Formin homology 2 domain containing 1, Formin homology 2 domain containing protein 1, Formin homology 2 domain-containing protein 1.

Background: The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.

Gen-ID: 29109