EEF2K Antikörper (pSer359) (Biotin)
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- Target Alle EEF2K Antikörper anzeigen
- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
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Bindungsspezifität
- pSer359
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EEF2K Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Sheep,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human EEF2k around the phosphorylation site of Ser359
- Isotyp
- IgG
- Top Product
- Discover our top product EEF2K Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
- Andere Bezeichnung
- EEF2k (EEF2K Produkte)
- Synonyme
- HSU93850 antikoerper, eEF-2K antikoerper, C86191 antikoerper, SMEF2K antikoerper, eEF-2 kinase antikoerper, cb365 antikoerper, fa04b08 antikoerper, wu:fa04b08 antikoerper, zgc:100973 antikoerper, eukaryotic elongation factor 2 kinase antikoerper, eukaryotic elongation factor-2 kinase antikoerper, EEF2K antikoerper, Eef2k antikoerper, eef2k antikoerper, LOC101930123 antikoerper
- Hintergrund
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Synonyms: EEF2K phospho S359, p-EEF2K phospho S359, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, eEF 2 kinase, eEF 2K, EEF2K protein, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, kinase eEF2K, SMEF2K, EF2K_HUMAN.
Background: Eukaryotic elongation factor 2 kinase (EEF2k) previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 (eEf2). Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors.
- Gen-ID
- 29904
- Pathways
- AMPK Signaling
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