UBR5 Antikörper (AA 11-120) (Biotin)

Produktnummer ABIN1700588

Produktdetails anti-UBR5 Antikörper (Biotin)

Target: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Bindungsspezifität: AA 11-120

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBR5 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu UBR5

Target: UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))

Andere Bezeichnung: UBR5 (UBR5 Produkte)

Hintergrund:

Synonyms: 4432411E13Rik, AW549941, C77315, D030042K14, DD5, E3 identied by dferential display, E3 ubiquitin protein ligase, HECT domain containing, 1, E3 ubiquitin-protein ligase, E3 ubiquitin-protein ligase UBR5, EDD 1, EDD, EDD, EDD1, FLJ11310, HECT domain-containing 1, hHYD, HYD, Hyperplastic discs protein homolog, KIAA0896, MGC57263, mKIAA0896, Progestin induced protein, Progestin-induced protein, Rat100, Ubiquitin protein ligase, Ubiquitin protein ligase E3 component n recognin 5, UBR5, UBR5_HUMAN.

Background: EDD is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Gen-ID: 51366

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway