GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) Antikörper (Biotin)

Produktnummer ABIN1700690

Produktdetails

Target: GC-Rich Promoter Binding Protein 1 (GPBP1)

Bindungsspezifität: AA 11-110

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPBP1/Vasculin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: GC-Rich Promoter Binding Protein 1 (GPBP1)

Andere Bezeichnung: GPBP1/Vasculin (GPBP1 Produkte)

Synonyme: MGC80437 antikoerper, Vasculin antikoerper, DKFZp459A203 antikoerper, GPBP antikoerper, SSH6 antikoerper, VASCULIN antikoerper, 1700034P14Rik antikoerper, AU019836 antikoerper, D230035M11Rik antikoerper, Gpbp antikoerper, mGPBP antikoerper, RGD1305492 antikoerper, GC-rich promoter binding protein 1 L homeolog antikoerper, GC-rich promoter binding protein 1 antikoerper, gpbp1.L antikoerper, gpbp1 antikoerper, GPBP1 antikoerper, Gpbp1 antikoerper

Hintergrund:

Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

Gen-ID: 65056