G6PC2 Antikörper (AA 31-130) (Biotin)

Produktnummer ABIN1700876

Produktdetails anti-G6PC2 Antikörper (Biotin)

Target: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Bindungsspezifität: AA 31-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser G6PC2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu G6PC2

Target: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Andere Bezeichnung: Glucose 6 phosphatase 2/IGRP (G6PC2 Produkte)

Synonyme: IGRP antikoerper, G6pc-rs antikoerper, Igrp antikoerper, g6pc2 antikoerper, igrp antikoerper, glucose-6-phosphatase catalytic subunit 2 antikoerper, glucose-6-phosphatase, catalytic, 2 antikoerper, glucose-6-phosphatase, catalytic, 2 S homeolog antikoerper, G6PC2 antikoerper, G6pc2 antikoerper, g6pc2.S antikoerper

Hintergrund:

Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

Gen-ID: 57818