GMEB1 Antikörper (AA 301-400) (Biotin)
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- Target Alle GMEB1 Antikörper anzeigen
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GMEB1 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GMEB1
- Isotyp
- IgG
- Top Product
- Discover our top product GMEB1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
- Andere Bezeichnung
- GMEB1 (GMEB1 Produkte)
- Synonyme
- MGC81052 antikoerper, GMEB1 antikoerper, si:ch211-245h7.5 antikoerper, pif96 antikoerper, p96pif antikoerper, MGC147529 antikoerper, P96PIF antikoerper, PIF96 antikoerper, 1110050A04Rik antikoerper, AI256615 antikoerper, AI481278 antikoerper, RGD1563208 antikoerper, glucocorticoid modulatory element binding protein 1 S homeolog antikoerper, glucocorticoid modulatory element binding protein 1 antikoerper, gmeb1.S antikoerper, GMEB1 antikoerper, gmeb1 antikoerper, Gmeb1 antikoerper
- Hintergrund
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Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.
Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
- Gen-ID
- 10691
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