Inversin Antikörper (AA 31-130) (Biotin)

Produktnummer ABIN1700884

Produktdetails anti-Inversin Antikörper (Biotin)

Target: Inversin (INVS)

Bindungsspezifität: AA 31-130

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Inversin Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Chimpanzee

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Inversin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Inversin

Target: Inversin (INVS)

Andere Bezeichnung: Inversin (INVS Produkte)

Synonyme: invs-a antikoerper, INVS antikoerper, MGC140477 antikoerper, inv antikoerper, NPH2 antikoerper, NPHP2 antikoerper, INV antikoerper, Nphp2 antikoerper, RGD1563359 antikoerper, wu:fe47e11 antikoerper, inversin S homeolog antikoerper, inversin antikoerper, Inversin antikoerper, invs.S antikoerper, INVS antikoerper, Bm1_38710 antikoerper, PTRG_09181 antikoerper, EAMY_RS33690 antikoerper, LOAG_11716 antikoerper, invs antikoerper, Invs antikoerper

Hintergrund:

Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.

Background: Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.

Gen-ID: 27130