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Thymopoietin Antikörper (AA 51-150) (Biotin)

TMPO Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700889
  • Target Alle Thymopoietin (TMPO) Antikörper anzeigen
    Thymopoietin (TMPO)
    Bindungsspezifität
    • 14
    • 13
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 64
    • 21
    • 16
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 6
    Kaninchen
    Klonalität
    • 59
    • 5
    Polyklonal
    Konjugat
    • 30
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Thymopoietin Antikörper ist konjugiert mit Biotin
    Applikation
    • 57
    • 24
    • 19
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LAP2
    Isotyp
    IgG
    Top Product
    Discover our top product TMPO Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Thymopoietin (TMPO)
    Andere Bezeichnung
    LAP2 alpha (TMPO Produkte)
    Synonyme
    LAP2 antikoerper, CMD1T antikoerper, LEMD4 antikoerper, PRO0868 antikoerper, TP antikoerper, lap2 antikoerper, LAP2beta antikoerper, 5630400D24Rik antikoerper, AI195756 antikoerper, AI606875 antikoerper, AW214352 antikoerper, AW547477 antikoerper, tmpo antikoerper, wu:fc26f12 antikoerper, wu:fd21f02 antikoerper, wu:fi29h05 antikoerper, thymopoietin antikoerper, thymopoietin S homeolog antikoerper, thymopoietin a antikoerper, TMPO antikoerper, Tmpo antikoerper, tmpo.S antikoerper, tmpoa antikoerper
    Hintergrund

    Synonyms: Isoforms beta/gamma, Lamina associated polypeptide 2 alpha, Lamina associated polypeptide 2, LAP2, Thymopoietin, Thymopoietin isoform alpha, TMPO, TP alpha, TP, LAP2 alpha, LAP2A_HUMAN.

    Background: The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (, _,_, and ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2 and LAP2_ associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2_ also binds to lamin B. LAP2 is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.

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