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Manic Fringe Antikörper (AA 221-321) (Biotin)

MFNG Reaktivität: Maus ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700893
  • Target Alle Manic Fringe (MFNG) Antikörper anzeigen
    Manic Fringe (MFNG) (MFNG)
    Bindungsspezifität
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-321
    Reaktivität
    • 28
    • 25
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 40
    • 4
    • 1
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Manic Fringe Antikörper ist konjugiert mit Biotin
    Applikation
    • 20
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Cow,Sheep,Horse,Chimpanzee
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG
    Isotyp
    IgG
    Top Product
    Discover our top product MFNG Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Manic Fringe (MFNG) (MFNG)
    Andere Bezeichnung
    Manic Fringe/MFNG (MFNG Produkte)
    Synonyme
    AW546563 antikoerper, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antikoerper, MFNG antikoerper, Mfng antikoerper
    Hintergrund

    Synonyms: 3-N-acetylglucosaminyltransferase manic fringe, Beta-1, Beta-1,3-N-acetylglucosaminyltransferase manic fringe, MFNG, MFNG_HUMAN, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.

    Background: Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

    Gen-ID
    4242
    Pathways
    Notch Signalweg
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