C1ORF216 Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN1700919

Produktdetails anti-C1ORF216 Antikörper (Biotin)

Target: C1ORF216 (Chromosome 1 Open Reading Frame 216 (C1ORF216))

Bindungsspezifität: AA 101-200

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1ORF216 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf216

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C1ORF216

Target: C1ORF216 (Chromosome 1 Open Reading Frame 216 (C1ORF216))

Andere Bezeichnung: C1orf216 (C1ORF216 Produkte)

Synonyme: 7530403E16Rik antikoerper, AI849033 antikoerper, RIKEN cDNA 5730409E04Rik gene antikoerper, chromosome 1 open reading frame 216 antikoerper, chromosome 1 open reading frame 216 S homeolog antikoerper, 5730409E04Rik antikoerper, C1orf216 antikoerper, c1orf216.S antikoerper

Hintergrund:

Synonyms: 5730409E04Rik, C1orf216, CA216_HUMAN, chromosome 1 open reading frame 216, hypothetical protein LOC127703, UPF0500 protein C1orf216.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf216 gene product has been provisionally designated C1orf216 pending further characterization.

Gen-ID: 127703