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GCAP1 Antikörper (AA 51-150) (Biotin)

GUCA1A Reaktivität: Maus, Ratte ELISA, WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701042
  • Target Alle GCAP1 (GUCA1A) Antikörper anzeigen
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Bindungsspezifität
    • 14
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 21
    • 17
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 34
    • 1
    Kaninchen
    Klonalität
    • 34
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GCAP1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 29
    • 16
    • 13
    • 13
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GCAP1
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Andere Bezeichnung
    GCAP1 (GUCA1A Produkte)
    Synonyme
    C6orf131 antikoerper, COD3 antikoerper, CORD14 antikoerper, GCAP antikoerper, GCAP1 antikoerper, GUCA antikoerper, GUCA1 antikoerper, dJ139D8.6 antikoerper, MGC84170 antikoerper, GUCA1A antikoerper, guca1a antikoerper, MGC146317 antikoerper, GC-A antikoerper, Gcap1 antikoerper, Guca1 antikoerper, mGCAP1 antikoerper, gcap1 antikoerper, guanylate cyclase activator 1A antikoerper, guanylate cyclase activator 1A L homeolog antikoerper, guanylate cyclase activator 1A (retina) antikoerper, guanylate cyclase activator 1a (retina) antikoerper, GUCA1A antikoerper, Guca1a antikoerper, guca1a.L antikoerper, guca1a antikoerper
    Hintergrund

    Synonyms: COD3, GCAP 1, GCAP, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activator 1A, Guanylate Cyclase Activator 1A, Guanylin 1, Guanylin 1, guanylyl cyclase activating protein 1, Guanylyl cyclase-activating protein 1, GUC1A_HUMAN, GUCA, GUCA1, GUCA1A, GUCA1A.

    Background: intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90 % similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.

    Gen-ID
    2978
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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