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FFAR1 Antikörper (AA 121-220) (Biotin)

FFAR1 Reaktivität: Human, Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701125
  • Target Alle FFAR1 Antikörper anzeigen
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reaktivität
    • 60
    • 30
    • 16
    • 5
    • 5
    • 3
    • 1
    Human, Maus
    Wirt
    • 59
    • 1
    • 1
    Kaninchen
    Klonalität
    • 60
    • 1
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FFAR1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 47
    • 20
    • 13
    • 13
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPR40
    Isotyp
    IgG
    Top Product
    Discover our top product FFAR1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Andere Bezeichnung
    GPR40 (FFAR1 Produkte)
    Synonyme
    FFAR1 antikoerper, GPR40 antikoerper, FFA1R antikoerper, GPCR40 antikoerper, Gpr40 antikoerper, free fatty acid receptor 1 antikoerper, FFAR1 antikoerper, Ffar1 antikoerper
    Hintergrund

    Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Gen-ID
    2864
    UniProt
    O14842
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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