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BLM Antikörper (AA 1201-1417) (Biotin)

BLM Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701166
  • Target Alle BLM Antikörper anzeigen
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1201-1417
    Reaktivität
    • 59
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 3
    • 2
    Kaninchen
    Klonalität
    • 62
    • 2
    Polyklonal
    Konjugat
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BLM Antikörper ist konjugiert mit Biotin
    Applikation
    • 46
    • 31
    • 13
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BLM/Blooms Syndrome Protein Blm
    Isotyp
    IgG
    Top Product
    Discover our top product BLM Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    Andere Bezeichnung
    BLM/Blooms Syndrome Protein Blm (BLM Produkte)
    Synonyme
    BS antikoerper, RECQ2 antikoerper, RECQL2 antikoerper, RECQL3 antikoerper, blm-A antikoerper, xBLM antikoerper, ORF1 antikoerper, Bloom syndrome RecQ like helicase antikoerper, Bloom syndrome RecQ like helicase S homeolog antikoerper, Bloom syndrome, RecQ like helicase antikoerper, BLM antikoerper, blm.S antikoerper, Blm antikoerper
    Hintergrund

    Synonyms: BLM, BLM_HUMAN, Bloom Syndrome, Bloom syndrome protein, Bloom syndrome RecQ helicase like, BS, DNA Helicase, DNA helicase RecQ like type 2, MGC126616, MGC131618, MGC131620, RECQ 2, RECQ like, RecQ like type 2, RecQ protein like 3, RecQ Protein-like 3, RECQ-2, RECQ-Like, RecQ-like type 2, RECQ2, RECQL 2, RECQL 3, RECQL-2, RECQL-3, RECQL2, RECQL3, type 2.

    Background: Bloom?s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, sun sensitivity, immunodeficiency and a predisposition to various cancers. The gene responsible for Bloom?s syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom?s syndrome patients. One characteristic of Bloom?s syndrome is an increased frequency of sister chromatid exchange (SCE). BLM has been shown to unwind G4 DNA, and a failure of this function is thought to be responsible for the increased rate of SCE. BLM is known to be translocated to the nucleus, where its ATPase activity is stimulated by both single- and double-stranded DNA. Mutations in the yeast SGS1, a homolog of BLM, are known to cause mitotic hyperrecombination similiar to that observed in Bloom?s cells.

    Gen-ID
    641
    Pathways
    DNA Reparatur
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