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EYA2 Antikörper (AA 201-300) (Biotin)

EYA2 Reaktivität: Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701245
  • Target Alle EYA2 Antikörper anzeigen
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 42
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 53
    • 3
    Kaninchen
    Klonalität
    • 54
    • 2
    Polyklonal
    Konjugat
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EYA2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 43
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EYA2
    Isotyp
    IgG
    Top Product
    Discover our top product EYA2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Andere Bezeichnung
    EYA2 (EYA2 Produkte)
    Synonyme
    EYA2 antikoerper, zgc:92279 antikoerper, eab1 antikoerper, Eab1 antikoerper, EAB1 antikoerper, EYA transcriptional coactivator and phosphatase 2 antikoerper, EYA2 antikoerper, eya2 antikoerper, Eya2 antikoerper
    Hintergrund

    Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

    Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

    Gen-ID
    2139
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