GPR124 Antikörper (AA 351-450) (Biotin)

Produktnummer ABIN1701283

Produktdetails anti-GPR124 Antikörper (Biotin)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Bindungsspezifität: AA 351-450

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR124 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 124

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Andere Bezeichnung: GPR124 (GPR124 Produkte)

Synonyme: TEM5 antikoerper, 8430414O08Rik antikoerper, 9530074E10Rik antikoerper, Tem5 antikoerper, mKIAA1531 antikoerper, MGC69043 antikoerper, si:dkey-208c22.2 antikoerper, GPR124 antikoerper, adhesion G protein-coupled receptor A2 antikoerper, adhesion G protein-coupled receptor A2 L homeolog antikoerper, G-protein coupled receptor 124 antikoerper, ADGRA2 antikoerper, Adgra2 antikoerper, adgra2.L antikoerper, adgra2 antikoerper, LOC616111 antikoerper

Hintergrund:

Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124, Adhesion G protein-coupled receptor A2, ADGRA2.

Background: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Gen-ID: 25960

UniProt: Q96PE1