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GALNS Antikörper (AA 1-100) (Biotin)

GALNS Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701288
  • Target Alle GALNS Antikörper anzeigen
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 53
    • 12
    • 12
    Human
    Wirt
    • 54
    • 2
    • 1
    Kaninchen
    Klonalität
    • 57
    Polyklonal
    Konjugat
    • 22
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GALNS Antikörper ist konjugiert mit Biotin
    Applikation
    • 43
    • 24
    • 19
    • 16
    • 13
    • 13
    • 13
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GALNS
    Isotyp
    IgG
    Top Product
    Discover our top product GALNS Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
    Andere Bezeichnung
    GALNS (GALNS Produkte)
    Synonyme
    GALNAC6S antikoerper, GAS antikoerper, GalN6S antikoerper, MPS4A antikoerper, mFLJ00319 antikoerper, galns antikoerper, zgc:158385 antikoerper, galactosamine (N-acetyl)-6-sulfatase antikoerper, galactosamine (N-acetyl)-6-sulfate sulfatase antikoerper, N-acetylgalactosamine-6-sulfatase antikoerper, galactosamine (N-acetyl)-6-sulfatase L homeolog antikoerper, GALNS antikoerper, Galns antikoerper, Celly_0425 antikoerper, galns.L antikoerper, galns antikoerper
    Hintergrund

    Synonyms: Chondroitinase, Chondroitinsulfatase, FLJ00319, FLJ17434, FLJ42844, FLJ98217, Galactosamine N acetyl 6 sulfate sulfatase, Galactose 6 sulfate sulfatase, GALNAC6S, GalNAc6S sulfatase, GAS, mFLJ00319, MPS4A, N acetylgalactosamine 6 sulfatase, N acetylgalactosamine 6 sulfate sulfatase, GALNS_HUMAN.

    Background: Chondroitinase is a 522 amino acid protein that localizes to the lysosome and functions as an exohydrolase that is essential for the degradation of glycosaminoglycans, keratan sulfate and chondroitin 6-sulfate. Using calcium as a cofactor, Chondroitinase, which exists as a disulfide linked oligomer, catalyzes the hydrolysis of the 6-sulfate group on target substrates. Defects in the gene encoding Chondroitinase are the cause of mucopolysaccharidosis type 4A (MPS4A), an autosomal recessive lysosomal storage disease that is characterized by the intracellular accumulation of keratan sulfate and chondroitin-6-sulfate and is associated with dental anomalies, short stature and, in some cases, death in the second or third decade of life.

    Gen-ID
    2588
    Pathways
    Glycosaminoglycan Metabolic Process
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