PRICKLE1 Antikörper (AA 551-650) (Biotin)
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- Target Alle PRICKLE1 Antikörper anzeigen
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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Bindungsspezifität
- AA 551-650
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRICKLE1 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Prickle
- Isotyp
- IgG
- Top Product
- Discover our top product PRICKLE1 Primärantikörper
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- Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
- Andere Bezeichnung
- Prickle (PRICKLE1 Produkte)
- Synonyme
- EPM1B antikoerper, RILP antikoerper, Rilp antikoerper, 1110058P22Rik antikoerper, AW215793 antikoerper, Prickle antikoerper, mpk1 antikoerper, XPk antikoerper, pk-B antikoerper, prickle antikoerper, prickle-B antikoerper, Prickle-b antikoerper, prickle planar cell polarity protein 1 antikoerper, prickle planar cell polarity protein 1 L homeolog antikoerper, prickle planar cell polarity protein 1 S homeolog antikoerper, PRICKLE1 antikoerper, Prickle1 antikoerper, prickle1.L antikoerper, prickle1.S antikoerper
- Hintergrund
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Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.
Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.
- Gen-ID
- 144165
- Pathways
- WNT Signalweg, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
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