SUMF1 Antikörper (AA 301-374) (Biotin)

Produktnummer ABIN1701379

Produktdetails anti-SUMF1 Antikörper (Biotin)

Target: SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))

Bindungsspezifität: AA 301-374

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUMF1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SUMF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SUMF1

Target: SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))

Andere Bezeichnung: SUMF1 (SUMF1 Produkte)

Synonyme: AAPA3037 antikoerper, FGE antikoerper, AA543204 antikoerper, AI463102 antikoerper, AI851573 antikoerper, sulfatase modifying factor 1 antikoerper, SUMF1 antikoerper, Sumf1 antikoerper

Hintergrund:

Synonyms: MGC150436, AAPA3037, C alpha formylglycine generating enzyme 1, C-alpha-formylglycine-generating enzyme 1, FGE, FGly generating enzyme, MGC131853, Sulfatase modying factor 1 [Precursor], Sulfatase-modying factor 1, SUMF1, SUMF1_HUMAN, UNQ3037.

Background: SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.

Gen-ID: 285362