Thrombin Activation Peptide Fragment 1 (AA 51-150) Antikörper (Biotin)
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- Target
- Thrombin Activation Peptide Fragment 1
- Bindungsspezifität
- AA 51-150
- Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Biotin
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Pig,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Thrombin Activation peptide fragment 1
- Isotyp
- IgG
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- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- Thrombin Activation Peptide Fragment 1
- Synonyme
- Cf-2 antikoerper, Cf2 antikoerper, FII antikoerper, thrombin antikoerper, coagulation factor II antikoerper, F2 antikoerper
- Hintergrund
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Synonyms: Activation peptide fragment 1, coagulation factor II, prothrombin, F2, Cf-2, Cf2, FII, F 2, coagulation factor II thrombin, Coagulation factor II, Coagulation factor II precursor, F2, Factor II, Factor-II, Prothrombin, prothrombin B-chain, PT, serine protease, THRB, THRB_HUMAN, Thrombin.
Background: Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets. The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin. Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail. Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin.
- Gen-ID
- 2147
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