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GNPTAB Antikörper (AA 1-100) (Biotin)

GNPTAB Reaktivität: Human ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701452
  • Target Alle GNPTAB Antikörper anzeigen
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Bindungsspezifität
    • 15
    • 14
    • 2
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser GNPTAB Antikörper ist konjugiert mit Biotin
    Applikation
    • 26
    • 26
    • 19
    • 5
    • 5
    • 5
    • 2
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human N-acetylglucosamine-1-phosphotransferase subunit alpha
    Isotyp
    IgG
    Top Product
    Discover our top product GNPTAB Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
    Andere Bezeichnung
    GNPTAB (GNPTAB Produkte)
    Synonyme
    si:ch211-234f20.3 antikoerper, wu:fd55d09 antikoerper, zgc:122985 antikoerper, zgc:158502 antikoerper, GNPTA antikoerper, ICD antikoerper, EG432486 antikoerper, mKIAA1208 antikoerper, RGD1564821 antikoerper, N-acetylglucosamine-1-phosphate transferase alpha and beta subunits antikoerper, N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits antikoerper, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta antikoerper, GNPTAB antikoerper, gnptab antikoerper, LOC100175423 antikoerper, Gnptab antikoerper
    Hintergrund

    Synonyms: N-acetylglucosamine-1-phosphotransferase subunit alpha, EC=2.7.8.17, GlcNAc-1-phosphotransferase subunits alpha/beta, GNPTA, GNPTA_HUMAN, Gnptab, KIAA1208, Stealth protein GNPTAB, UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta.

    Background: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

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