FOXH1 Antikörper (AA 41-140) (Biotin)

Produktnummer ABIN1701505

Produktdetails anti-FOXH1 Antikörper (Biotin)

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Bindungsspezifität: AA 41-140

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXH1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXH1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FOXH1

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Andere Bezeichnung: FOXH1 (FOXH1 Produkte)

Synonyme: FOXH1 antikoerper, XFast-1 antikoerper, fast-1 antikoerper, fast1 antikoerper, foxh1a antikoerper, xfast1 antikoerper, xfoxh1 antikoerper, FAST-1 antikoerper, FAST1 antikoerper, Fast1 antikoerper, Fast2 antikoerper, fast-2 antikoerper, SUR antikoerper, fast antikoerper, fe26b06 antikoerper, schmalspur antikoerper, wu:fe26b06 antikoerper, wu:fi30c08 antikoerper, wu:fi32b01 antikoerper, forkhead box H1 antikoerper, forkhead box H1 L homeolog antikoerper, FOXH1 antikoerper, foxh1 antikoerper, Foxh1 antikoerper, foxh1.L antikoerper

Hintergrund:

Synonyms: FAST 1, Fast 2, Fast-1, Fast-2, FAST1, Fast2, Forkhead activin signal transducer 1, Forkhead activin signal transducer 2, Forkhead box H1, Forkhead box protein H1, FOX H1, FOXH 1, FOXH1, FOXH1_HUMAN, hFAST 1, hFAST-1, hFAST1, Human homolog of Xenopus forkhead activin signal transducer 1, TGF beta/Activin signal transducer FAST1.

Background: Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß, and activin, indicating that these FAST proteins mediate TFGß, induced signal transduction (3).

Gen-ID: 8928

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling