CMKLR1 Antikörper (AA 151-250) (Biotin)
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- Target Alle CMKLR1 Antikörper anzeigen
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human, Maus, Ratte, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CMKLR1 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Schwein, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse CMKLR1
- Isotyp
- IgG
- Top Product
- Discover our top product CMKLR1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Andere Bezeichnung
- CMKLR1 (CMKLR1 Produkte)
- Synonyme
- CHEMERINR antikoerper, ChemR23 antikoerper, DEZ antikoerper, RVER1 antikoerper, Gpcr27 antikoerper, mcmklr1 antikoerper, si:ch211-240b21.3 antikoerper, CMLKR1 antikoerper, Cmklr-1 antikoerper, GPCR antikoerper, chemerin chemokine-like receptor 1 antikoerper, chemokine-like receptor 1 antikoerper, CMKLR1 antikoerper, Cmklr1 antikoerper, cmklr1 antikoerper
- Hintergrund
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Synonyms: DEZ, Gpcr27, ChemR23, mcmklr1, Chemokine-like receptor 1, G-protein coupled receptor DEZ, Cmklr1
Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism.
- Gen-ID
- 14747
- UniProt
- P97468
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