IBA57 Antikörper (AA 131-230) (Cy3)

Produktnummer ABIN1703252

Produktdetails anti-IBA57 Antikörper (Cy3)

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Bindungsspezifität: AA 131-230

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBA57 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf69

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IBA57

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Andere Bezeichnung: C1orf69 (IBA57 Produkte)

Synonyme: C1orf69 antikoerper, 4930543L23Rik antikoerper, A230051G13Rik antikoerper, zgc:153540 antikoerper, IBA57 homolog, iron-sulfur cluster assembly antikoerper, IBA57 antikoerper, Iba57 antikoerper, iba57 antikoerper

Hintergrund:

Synonyms: C1orf69, CA069_HUMAN, CAF17_HUMAN, FLJ12734, FLJ13849, IBA57, IBA57 iron sulfur cluster assembly homolog, IBA57 iron sulfur cluster assembly homolog S. cerevisiae, Iron sulfur cluster assembly factor for biotin synthase and aconitase like, Iron-sulfur cluster assembly factor homolog, mitochondrial, Mitochondrial proteins with a mass of 57 kDa, Putative transferase C1orf69, Putative transferase C1orf69 mitochondrial, Putative transferase CAF17, mitochondrial.

Background: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Gen-ID: 200205