BSPRY Antikörper (AA 251-350) (Cy5)

Produktnummer ABIN1703832

Produktdetails anti-BSPRY Antikörper (Cy5)

Target: BSPRY (B-Box and SPRY Domain Containing (BSPRY))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BSPRY Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BSPRY

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BSPRY

Target: BSPRY (B-Box and SPRY Domain Containing (BSPRY))

Andere Bezeichnung: BSPRY (BSPRY Produkte)

Synonyme: B-box and SPRY domain containing antikoerper, BSPRY antikoerper, Bspry antikoerper

Hintergrund:

Synonyms: B box and SPRY domain containing, B box and SPRY domain containing protein, B box and SPRY domain-containing protein,B-box and SPRY domain containing, Bspry, BSPRY_HUMAN, FLJ20150, Zetin 1.

Background: BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.