CATSPER3 Antikörper (AA 201-300) (Cy5)

Produktnummer ABIN1703859

Produktdetails anti-CATSPER3 Antikörper (Cy5)

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CATSPER3 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CATSPER3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CATSPER3

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Andere Bezeichnung: CATSPER3 (CATSPER3 Produkte)

Synonyme: CATSPER3 antikoerper, CACRC antikoerper, 4921522D01Rik antikoerper, cation channel sperm associated 3 antikoerper, cation channel, sperm associated 3 antikoerper, CATSPER3 antikoerper, Catsper3 antikoerper

Hintergrund:

Synonyms: cation channel sperm-associated protein 3, calcium channel repeat containing 1, putative ion channel CatSper3, cav-like protein, one-repeat calcium channel-like protein, CATSPER3, CACRC, Cav-like protein, CACRC, Cation channel, sperm associated 3, CTSR3_HUMAN, putative ion channel CatSper3.

Background: CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

Gen-ID: 347732

UniProt: Q86XQ3