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GEMIN6 Antikörper (AA 21-120) (Cy5)

GEMIN6 Reaktivität: Human, Ratte WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1703935
  • Target Alle GEMIN6 Antikörper anzeigen
    GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
    Bindungsspezifität
    • 14
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 29
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 25
    • 4
    Kaninchen
    Klonalität
    • 27
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GEMIN6 Antikörper ist konjugiert mit Cy5
    Applikation
    • 24
    • 12
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Gemin 6
    Isotyp
    IgG
    Top Product
    Discover our top product GEMIN6 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
    Andere Bezeichnung
    Gemin 6 (GEMIN6 Produkte)
    Synonyme
    2610019B15Rik antikoerper, 2810470M17Rik antikoerper, gemin6 antikoerper, gem nuclear organelle associated protein 6 antikoerper, gem (nuclear organelle) associated protein 6 antikoerper, gem nuclear organelle associated protein 6 S homeolog antikoerper, GEMIN6 antikoerper, Gemin6 antikoerper, gemin6.S antikoerper
    Hintergrund

    Synonyms: FLJ23459, Gemin6, Gemin-6, Gem nuclear organelle associated protein 6, Gem-associated protein 6, GEMI6, GEMI6_HUMAN, Gemin-6, GEMIN6, SIP2.

    Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).

    Gen-ID
    79833
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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